儿童病毒性心肌炎心脏储备功能的初步研究——毕业论文4.docVIP

儿童病毒性心肌炎心脏储备功能的初步研究霍俊明肖守中2谢梅兰2肖子夫2400014，重庆重庆医科大学附属儿童医院心脏中心400044，重庆重庆大学生物工程学院目的应用研究病毒性心肌炎儿童的心脏储备功能变化。方法采用运动心力监测仪及心脏储备软件，在静息状态下记录病毒性心肌炎患儿（n=）和同龄健康儿童（n=）心音图，~3岁，~7岁两个年龄段，测量第1心音幅值（S1）、第2心音幅值（S2）、舒张期（D）和收缩期（S）时限，计算S1/S2比值、D/S比值。结果~3岁组分别为：1.36±0.05，1.22±0.14 vs 1.50±0.11，1.33±0.12；~7岁组分别为：1.44±0.05，1.29±0.11 vs 1.63±0.13，1.45±0.16）；两组比较，差异有统计学意义(p0.01)。结论病毒性心肌炎患儿心脏收缩和舒张功能均降低。[关键词]病毒性心肌炎儿童S1/S2；舒张期/收缩期时限比心脏储备 [] R725.4 [文献标志码] A [文章编号] Study on cardiac reserve in children with viral myocarditis Huo Junming1 Yi Qijian1 Xiao Shouzhong2 Xie Meilan2 Xiao Zhifu2 (1Heart center, Children’s hospital, Chongqing medical university, Chongqing 400014 China, 2Bioengineering College of Chongqing University, Chongqing, 400044 China) [Abstract] Objective To investigate cardiac reserve in children with viral myocarditis (VMC).Methods The phonocardiograms of children with viral myocarditis (n=60) and healthy control (n=60) were recorded in rest state by using the cardiac contractility monitor and cardiac reserve software produced by Bioengineering College of Chongqing University and Chongqing BoJing Medical Informatics Institute recently. Then the amplitude of the first (S1) and second heart sound(S2), the duration of diastole(D) and systole(S) were measured, ratio of the amplitude of first and second heart sound (S1/S2) and ratio of the duration of diastolic and systolic (D/S) were calculated and compared between 1~3 years old group and ~7 years old group.Results Compared with control group,the ratios of S1/S2 and D/S were all decreased(1.36±0.05，1.22±0.14 vs 1.50±0.11，1.33±0.12 in 1~3 year old group,and 1.44±0.05，1.29±0.11 vs 1.63±0.13，1.45±0.16 in ~7 years old group,respectively) in VMC group(P0.01).Conclusion The system of cardiac contractility monitor and cardiac reserve software can quantify the cardiac function. Cardiac reserve is reduced in systolic function and diastolic function in children with VMC. [Key words] vital myocarditis;children;S1/S2;D/S;ca