Balanced Propofol Sedation in Patients Undergoing EUS-FNA A Pilot Study to Assess Feasibility and Safety英文文献资料.docVIP
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Balanced Propofol Sedation in Patients Undergoing EUS-FNA A Pilot Study to Assess Feasibility and Safety英文文献资料
HindawiPublishingCorporation
DiagnosticandTherapeuticEndoscopy
Volume2011,ArticleID542159,5pages
doi:10.1155/2011/542159
ClinicalStudy
BalancedPropofolSedationinPatientsUndergoingEUS-FNA:
APilotStudytoAssessFeasibilityandSafety
N.Pagano,
A.Carlino,
1
M.Arosio,
2
F.Romeo,
1
1
G.Rando,
1
1
G.DelConte,
andA.Repici
1
1
1
G.Strangio,
E.Vitetta,
A.Malesci,
1
1
2
DipartimentodiGastroenterologia,IstitutoClinicoHumanitas,ViaManzoni56,MI,20089Rozzano,Milano,Italy
DipartimentodiAnestesiologia,IstitutoClinicoHumanitas,ViaManzoni56,MI,20089Rozzano,Milano,Italy
CorrespondenceshouldbeaddressedtoN.Pagano,nico.pagano@humanitas.it
Received31January2011;Accepted16May2011
AcademicEditor:P.J.O’Dwyer
Copyright?2011N.Paganoetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense,
whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited.
Introductionandaims.Balancedpropofolsedation(BPS)administeredbygastroenterologistshasgainedpopularityinendoscopic
procedures.Fewstudiesexistaboutthesafetyofthisapproachduringendosonographywith?neneedleaspiration(EUS-FNA).
WeassessedthesafetyofBPSinEUS-FNA.Materialsandmethods.112consecutivepatients,referredtoourunittoperformEUS-
FNA,fromFebruary2008toDecember2009,weresedatedwithBPS.Asecondgastroenterologistadministeredthedrugsand
monitorizedthepatient.Results.Allthe112patients(62males,meanage58.35)completedtheexamination.Themeandoseof
midazolamandpropofolwas,respectively,of2.1mg(range1–4mg)and350mg(range180–400).Allpatientsreceivedoxygen
withamean?uxof4liter/minute(range2–6liters/minute).Themeanrecoverytimeafterprocedurewas25minutes(range18–45
minutes).Nomajorcomplicationsrelatedtosedationwereregisteredduringallprocedures.Theoxygensaturationofallpatients
neverreducedtolessthan85%.Bloodsystolicpressureduringandaftertheprocedureneverreducedtolessthan100mmHg.
Conclusions.InourexperienceBPSadministeredbynon-anaesthesiologistsprovidedsafeandsuccessfulsedationinpatients
undergoingEUS-FN
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