- 1、本文档共22页,可阅读全部内容。
- 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
课件-国外大学细胞生物学课件-英文3.bioy
Common fatal genetic disease Phenotype: thick, sticky mucus ?respiratory congestion ?breeding ground for infection-causing bacteria ?blocks pancreas function Cystic Fibrosis is caused by mutations in CFTR, an anion channel in the apical surface of epithelial cells of the lung, pancreas, intestine and sweat glands. Mutations lead to disruption of fluid secretion into the lung (sticky mucus that cannot be cleared Early sign of the disease: saltiness of skin because fluid secretion works in conjunction with other ion transporters in epithelial cells. * Cystic Fibrosis W2011 D103 Cell Biology - lecture 3 ? Suetterlin and MacGregor - all rights reserved. * Important concepts, lecture 3 Molecule transport across a membrane is mediated by transmembrane proteins Carriers/transporters (eg GLUT1) high specificity, saturable active and passive transport is possible Undergo conformational change during the transport of molecules Pumps/ATPase (MDR-1)? energy from ATP hydrolysis is converted into mechanical work such as ion transport against their electrochem. gradient) Ion channels (see lecture 4) Directions of transport: Transport down the electrochemical gradient is passive and does not require energy Transport against the electrochemical gradient requires energy ATP hydrolysis (Na/K pump), light-driven) “ride along” (syn- and antiport) taking advantage of the potential energy of other molecules. membrane potential: voltage difference across a membrane which is due to a slight misbalance of ions. W2011 D103 Cell Biology - lecture 3 ? Suetterlin and MacGregor - all rights reserved. * * * * * * * * * * * * * * * * * * * * * W2011 D103 Cell Biology - lecture 3 ? Suetterlin and MacGregor - all rights reserved. W2011 D103 Cell Biology - lecture 3 ? Suetterlin and MacGregor - all rights reserved. W2011 D103 Cell Biology - lecture 3 ? Suetterlin and MacGregor - all rights reserved. W2011 D103 Cell Biology - lecture 3 ? Suetterlin and MacGregor - all rights reserved.
您可能关注的文档
- 课件-高血压病管理ppt课件.pptx
- 课件-高血压的非药物治疗ppt课件.ppt
- 课件-高血压的护理.ppt
- 课件-高血压ppt课件幻灯片.ppt
- 课件-高血压合并左心室肥厚诊治专家共识.ppt
- 课件-高血压固定复方制剂新进展.ppt
- 课件-高血压护理查房.ppt
- 课件-高血压脑出血护理ppt课件.ppt
- 课件-高血脂的饮食疗法.pptx
- 课件-高血压医学课件.ppt
- 第6课表格的使用及设计课件--广东省阳江市粤教版七年级信息技术下册.pptx
- 美国哈希仪器专用试剂使用说明.pptx
- 像高手一样发言 七种常见工作场景的说话之道 读书笔记思维导图PPT模板下载.pptx
- 中国烹饪概论(第二版)-金洪霞-电子课件PPT (4)[37页].pptx
- 环境工程制图与CAD 课件 第九章环境工程专业绘图实训.pptx
- 三年级上册数学第二单元1课时课件《两位数加、减两位数PPT课件》.pptx
- 人教版小学数学一年级下册第六单元《100以内的加法和减法》课件(知识点全面).pptx
- 学前儿童社会性发展的影响因素.pptx
- 人教版数学一年级下册《100以内数的认识》PPT.pptx
- 健康领域幼儿PPT课件.pptx
文档评论(0)