结核_伤寒_菌痢_阿米巴_性传播疾病.ppt

胃kaposi肉瘤 临床病理联系 ????潜伏期较长，可潜伏数月－10余年后发病。AIDS病程分三阶段：??????? 早期（急性期）：感染3-6周后出现咽痛、发热、肌痛，2-3W后可自行缓解； 中期（慢性期）：无明显症状或全身淋巴结肿大、发热、乏力、皮疹等。 后期（危险期）：免疫缺陷，持续发热、乏力、消瘦和腹泻，各种机会感染、继发性肿瘤、神经系统症状。??? ? 结局：预后差 * Swelling of the lymphoid tissue period: (1st week ) especially the Peyer’s patches. It appear button-like protrusion, oval shaped long grey-red plaques. * Necrosis period : 2nd week of the onset. Necrosis begins in the affected patches and may well represent a delayed hypersensitivity reaction to the bacteria antigen. * Ulceration period:3rd week of the onset The overlying mucosa of the necrotic areas slough off, leaving ulcers. The ulcer running along the axis of the intestine. * Healing 4-5weeks: cell immunity chronic bacterium carrier Intestinal hemorrhage and perforation: occur during the 2nd or 3rd week of typhoid. fever. Pneumonia: often in children * Early stage------- acute catarrhal inflammation. Pseudomembranous inflammation Gross: Greyish white, dirty greenish Microscopically: fibrin, neutrophils Necrotic mucous membrane Ulcer formation—map shaped Clinically: abdominal cramps, diarrhea (stool contains blood, mucus, pus) severe cases; fever, vomiting, dehydration * 临床表现：腹部紧张，腹泻（含血，粘液，脓液）； 严重者高烧，呕吐，脱水 * Characteristic features: Abrupt onset Mild pathological changes in intestines: a catarrhal inflammation or follicular enteritis. Severe systemic toxic symptoms-shock, respiratory failure, etc. Occurs mostly in children. * Neisseria gonorrhoeae (G- diplococcus) * * * * * The 1st 3 weeks: the primary lesion －hard chancre location: usually on the penis, vulva or vagina. G: hard chancre: a raised button-like hard nodule with shallow ulceration, 1~2cm in diameter. M: peri-and endarteritis with diffuse monouclear infiltrate * * * * * infiltration of the lymphocytes and plasma cells begins around the vasa vasorum and ex