心房颤动的药物治疗进展_百度文库.doc

[7]Park SJ ,On YK ,Kim JS ,et al．Transforming growth factor β1-mediated atrial fibrotic activity and the recovery of atrial mechanical contraction after surgical maze procedure [J ]．Int J Cardiol , 2013,164(2:232-237．[8]Ｒahmutula D ,Marcus GM ,Wilson EE ,et al．Molecular basis of selective atri-al fibrosis due to overexpression of transforming growth factor-β1[J ]．Cardio-vasc Ｒes ,2013,99:769-779． [9]Yuan SM ,Jing H．Cardiac pathologies in relation to Smad-dependent pathways [J ]．Interact Cardiovasc Thorac Surg ,2010,11(4:455-460． [10]Polyakova V ,Miyagawa S ,Szalay Z ,et al．Atrial extracellular matrix remodel-ling in patients with atrial fibrillation [J ]．J Cell Mol Med ,2008,12(1:189-208． [11]Gautel M．The sarcomeric cytoskeleton :who picks up the strain [J ]．Curr Opin Cell Biol , 2011,23(1:39-46．[12]陈唐葶,周翔,王立群,等．急性心肌缺血大鼠心肌α辅肌动蛋白含量变化 及其与心功能的关系[J ]．南方医科大学学报, 2011,31(6:970-974．[13]Virel A ,Backman L．Molecular evolution and structure of alpha-actinin [J ]． Mol Biol Evol , 2004,21(6:1024-1031．[14]Isobe Y ,Warnert FD ,Flemanski LF．Three-dimensional immunogold localiza-tion of α-actinin within the cytoskeletal networks of cultured cardiac muscle and non-muscle cells [J ]．Proc Natl Acad Sci USA ,1988,85(18:6758-6762．[15]Mills MA ,Yang N ,Weinberger ＲP ,et al．Differential expression of the actin-binding proteins ,α-actinin-2and 3,in different species :implication for the e-volution of functional redundancy [J ]．Hum Mol Genet ,2001,10(13:1335-1346． [16]Shams H ,Golji J ,Mofrad MＲ．A molecular trajectory of α-actinin activation [J ]．Biophys J ,2012,103(10:2050-2059． [17]Lu L ,Timofeyev V ,Li N ,et al．Alpha-actinin2cytoskeletal protein is required for the functional membrane localization of a Ca 2+activated K +channel (SK2channel [J ]．Proc Natl Acad Sci USA , 2009,106(43:18402-18407．[18]Bakin AV ,Safina A ,Ｒinehart C ,et al．A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells [J ]．Mol Biol Cell , 2004,15(10:4682-4